Investigators have found that mutations in oncogenes are generally found to concentrate at a small number of positions within the protein coding sequence of the parent proto-oncogene. Mutations in tumor suppressor genes are found at many positions within the coding sequence of the tumor suppressor gene. Explain how you would account for this finding?

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Investigators have found that mutations in oncogenes are generally found to concentrate at a small number of positions within the protein coding sequence of the parent proto-oncogene. Mutations in tumor suppressor genes are found at many positions within the coding sequence of the tumor suppressor gene. Explain how you would account for this finding?

 

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